Type of Credit: Elective
Credit(s)
Number of Students
闡述離子通道在生物體上生理功能、藥理作用和病理病因之重要角色,並討論離子通道產生缺陷時,如藥毒物誘發、基因突變等,導致人體或其他動物病變之相關性。
能力項目說明
1.培育具統合分析、創新思考及解決問題之能力,兼備學術倫理與團隊合作精神。
2. 培養離子通道及疾病相關專業知識人才。
3. 英文閱讀及書寫能力。
課程主題/Topic |
|
Introduction |
|
Properties of Ion channels |
|
Neuronal signaling |
|
Electrophysiological recording |
|
Optical control of ion channels |
|
Paper presentation and discussion |
|
Na+ channel function, deficits and diseases |
|
期中評量 |
|
Correlating Ca++ channel deficits and diseases |
|
Correlating K+ channel deficits and diseases |
|
Correlating Cl- channel deficits and diseases |
|
Cation image and measurement |
|
Paralysis and Epilepsy |
|
Myotonic muscular dystrophy |
|
Long QT syndrome |
|
Paper presentation and discussion |
筆試50%; 討論30%; 課堂表現20%。
1.授課教授之隨堂講義。2. Frances M. Ashcroft, Ion Channels and Disease, Academic Press, 2000。